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Anxiety Among Perinatal Women During COVID-19 More Likely for Those Without...

Many women enter pregnancy with a pre-existing diagnosis of anxiety. Pregnancy itself can prompt worry about the health of the fetus and newborn, one’s health and the experience of childbirth. The...

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Neurological Soft Signs in Adolescents Linked to Brain Structure Alterations

The presence of neurological soft signs (NSS) in children and adolescents—minor deviations from the norm in motor performance and sensory-motor integration—appears to be an unspecific but sensitive...

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Novel Localization of MS-related Depression May Allow Therapeutic Brain...

Depression is one of the most common and debilitating complications reported by patients with multiple sclerosis (MS)—not just because of poorer health-related quality of life, but because the disease...

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Common Brain Network Identified for Multiple Psychiatric Disorders May...

Psychiatric disorders are typically studied individually, even though up to half of the patients meet the criteria for multiple disorders. Genomic and epidemiologic evidence suggests different...

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Physical, Cognitive Decline Accelerated in People With Late-Life Depression

Emerging evidence suggests cellular senescence is a hallmark of aging. Cells lose their proliferative capacity, become resistant to apoptosis, and develop a senescence-associated secretory phenotype...

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Ketamine Is Noninferior to ECT for Nonpsychotic Treatment-resistant Major...

Ketamine, administered intravenously at a subanesthetic dose, is being used increasingly often for patients with treatment-resistant major depressive disorder. It can lead to transient changes in...

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Neuroimaging Abnormalities Across Substance Use Disorders Map to a Common...

In 2023, a Brigham and Women’s Hospital team published evidence in Nature Human Behaviour that six psychiatric disorders map to a common brain network. The results suggested neuromodulation targets for...

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Effects of Modafinil on Cognition and Sleep Quality in Affectively Stable...

Most patients with bipolar disorder experience circadian dysfunction and deficits in attention, verbal memory, and executive functioning, even during periods of euthymia. Katherine E. Burdick, PhD,...

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Review: Mental Health Over the Menopause Transition

A 1959 paper in the Journal of the American Medical Association described menopause as a “rather unpleasant and possibly dangerous” period of life and presented what became the first widely used...

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Treatment of Depression/Anxiety in Osteoarthritis Linked to Better...

Depression and anxiety are common comorbidities of osteoarthritis (OA) of the hip or knee, yet surprisingly, little is known about how pharmacologic treatment for these conditions affects...

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